The CACNG5 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CACNG5. This antibody recognizes Human, Mouse, and Rat antigen. The CACNG5 Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
Description: Thought to stabilize the calcium channel in an inactivated (closed) state.
Function: Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity).
Subunit Structure: The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma. Acts as an auxiliary subunit for AMPA-selective glutamate receptors (AMPARs). Found in a complex with GRIA1, GRIA2, GRIA3, GRIA4, CNIH2, CNIH3, CACNG2, CACNG3, CACNG4, CACNG7 and CACNG8. Interacts with GRIA1, GRIA2, GRIA3 and GRIA4 (By similarity).
Similarity: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily